Recombinant Mouse Dendritic Cell Inflammatory Protein-1/CXCL3 (Mouse DCIP-1/CXCL3)_C230535

Description

CXCL3, also known as DCIP1 in mouse, CINC2 in rat, and GROγ in humans, is belonging to the CXC chemokine family. The amino acid sequence of mouse CXCL3 is 57 % identical to human CXCL3. CXCL3 plays a role in inflammation and exert its effects
on endothelial cells in an autocrine fashion. Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils. CXCL3 was reportedly associated with the
invasion and metastasis of various malignancies. As a member of the chemokine family, CXCL3 was previously known to participate in many pathophysiological events. CXCL3 was found to be upregulated in aggressive cancer cells.

 

Product Properties

Synonyms
chemokine (C-X-C motif) ligand 3, CINC-2, CINC-2b, CXCL3, Dcip1, Gm1960, GRO gamma, GRO3 oncogene, GRO3, GROG, GRO-gamma, Growth-regulated protein gamma, Macrophage inflammatory protein 2-beta, MGSA gamma, MIP2B, MIP-2b, MIP2-beta, SCYB3
Accession
Q6W5C0
GeneID
330122

Source
E.coli-derived mouse DCIP-1/CXCL3 protein, Ala28-Ser100.

Molecular Weight
Approximately 7.9 kDa.
AA Sequence

AVVASELRCQ CLNTLPRVDF ETIQSLTVTP PGPHCTQTEV IATLKDGQEV CLNPQGPRLQ IIIKKILKSG KSS

Tag
None
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.

Purity
>97% by SDS-PAGE and HPLC analyses.
Biological Activity
The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100 ng/ml. Fully biologically active when compared to standard.

Endotoxin
< 1.0 EU per 1μg of the protein by the LAL method.

Formulation
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.

Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

 

Shipping and Storage

The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions

1. Avoid repeated freeze-thaw cycles.
2. For your safety and health, please wear lab coats and disposable gloves for operation.
3. For research use only!

Recombinant Mouse Dendritic Cell Inflammatory Protein-1/CXCL3 (Mouse DCIP-1/CXCL3)_C230535

Product form

SKU: C230535E

$179.00

      • Tell a unique detail about this product

      Description

      CXCL3, also known as DCIP1 in mouse, CINC2 in rat, and GROγ in humans, is belonging to the CXC chemokine family. The amino acid sequence of mouse CXCL3 is 57 % identical to human CXCL3. CXCL3 plays a role in inflammation and exert its effects
      on endothelial cells in an autocrine fashion. Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils. CXCL3 was reportedly associated with the
      invasion and metastasis of various malignancies. As a member of the chemokine family, CXCL3 was previously known to participate in many pathophysiological events. CXCL3 was found to be upregulated in aggressive cancer cells.

       

      Product Properties

      Synonyms
      chemokine (C-X-C motif) ligand 3, CINC-2, CINC-2b, CXCL3, Dcip1, Gm1960, GRO gamma, GRO3 oncogene, GRO3, GROG, GRO-gamma, Growth-regulated protein gamma, Macrophage inflammatory protein 2-beta, MGSA gamma, MIP2B, MIP-2b, MIP2-beta, SCYB3
      Accession
      Q6W5C0
      GeneID
      330122

      Source
      E.coli-derived mouse DCIP-1/CXCL3 protein, Ala28-Ser100.

      Molecular Weight
      Approximately 7.9 kDa.
      AA Sequence

      AVVASELRCQ CLNTLPRVDF ETIQSLTVTP PGPHCTQTEV IATLKDGQEV CLNPQGPRLQ IIIKKILKSG KSS

      Tag
      None
      Physical Appearance
      Sterile Filtered White lyophilized (freeze-dried) powder.

      Purity
      >97% by SDS-PAGE and HPLC analyses.
      Biological Activity
      The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100 ng/ml. Fully biologically active when compared to standard.

      Endotoxin
      < 1.0 EU per 1μg of the protein by the LAL method.

      Formulation
      Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.

      Reconstitution
      We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

       

      Shipping and Storage

      The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
      Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

       

      Cautions

      1. Avoid repeated freeze-thaw cycles.
      2. For your safety and health, please wear lab coats and disposable gloves for operation.
      3. For research use only!

      © 2024 Arcegen, Powered by Shopify

      • American Express
      • Apple Pay
      • Diners Club
      • Discover
      • Google Pay
      • Mastercard
      • Shop Pay
      • Visa

      Login

      Forgot your password?

      Don't have an account yet?
      Create account