Description
Transforming growth factor-beta 1 (TGF-β1) is a major pluripotential cytokine with a pronounced immunosuppressive effect. TGF-β1 is a key regulator of diverse biological processes in many tissues and cell types, its can be tumorsuppressive through the activation of the Smadmediated signaling pathway.
Product Properties
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Synonyms
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CEDLAP, DPD1, latency-associated peptide, TGF beta, TGF beta1
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Uniprot No.
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P01137
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Source
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HEK293-derived Human TGF-β1, Ala279-Ser390.
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Molecular Weight
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The protein has a predicted 12.8 kDa
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Purity
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> 95% as determined by SDS-PAGE.
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Biological Activity
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Measured by the (CAGA)12—luciferase reporter assay. The EC50 for this effect is 1.092 ng/mL.
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Endotoxin
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< 0.01 EU per 1μg of the protein by the LAL method.
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Formulation
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Dissolved in sterile PBS buffer.
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Concentration
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0.5 mg/ml
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Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1. Avoid repeated freeze-thaw cycles.
2. For your safety and health, please wear lab coats and disposable gloves for operation.
3. For research use only!
