Description
Description
GDF-15,Placental Transforming Growth Factor beta, Prostate-derived Factor, and Placental Bone Morphogenetic Protein, is a divergent member of the Transforming Growth Factor beta (TGF-beta ) superfamily
Product Properties
|
Synonyms
|
Growth Differentiation Factor 15,MIC-1
|
|
Uniprot No.
|
Q99988
|
|
Source
|
Human GDF-15 Protein is expressed from E. coli.It contains Ala197-Ile308
|
|
Molecular Weight
|
Predicted molecular mass of approximately 12 kDa in SDS-PAGE under reducing condition.
|
|
Biological Activity
|
Measured by its binding ability in a functional ELISA. When rHuGDF-15/MIC-1 is used at 0.5
µg/mL, the concentration of Recombinant Human Activin RIB/ALK-4 Fc Chimera that produces 50% of the optimal binding response is approximately 0.5-3 μg/mL.
|
|
Purity
|
> 95% as determined by SDS-PAGE.
|
|
Endotoxin
|
<0.1 EU per 1μg of the protein by the LAL method.
|
|
Formulation
|
Lyophilized from 0.2 µm filtered concentrated solution in 4 mM HCl.
|
|
Reconstitution
|
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile 4 mM HCl to a concentration of 0.5 mg/mL. Further dilutions should be made in appropriately buffered solutions.
|
Shipping and Storage
The product should be stored at -25~-15℃ for 1 year from date of receipt.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.
